Gerhard Wiche Selected Research

Plectin

3/2022	Correction to: Plectin ensures intestinal epithelial integrity and protects colon against colitis.
2/2022	Correction: Plectin ensures intestinal epithelial integrity and protects colon against colitis.
1/2021	Plectin ensures intestinal epithelial integrity and protects colon against colitis.
1/2021	Identifying Plectin Isoform Functions through Animal Models.
1/2018	Plectin controls biliary tree architecture and stability in cholestasis.
1/2017	An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin.
12/2015	The cytolinker plectin regulates nuclear mechanotransduction in keratinocytes.
8/2015	Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle.
6/2015	Keratins Stabilize Hemidesmosomes through Regulation of β4-Integrin Turnover.
6/2015	Mutation in exon 1a of PLEC, leading to disruption of plectin isoform 1a, causes autosomal-recessive skin-only epidermolysis bullosa simplex.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Gerhard Wiche Research Topics

Disease

11	Muscular Dystrophies (Muscular Dystrophy) 08/2015 - 06/2002
8	Epidermolysa bullosa simplex and limb girdle muscular dystrophy 01/2021 - 06/2002
8	Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara) 12/2015 - 01/2002
4	Neoplasms (Cancer) 01/2017 - 11/2010
3	Colitis 03/2022 - 01/2021
2	Wounds and Injuries (Trauma) 06/2015 - 08/2006
2	Epidermolysis Bullosa 06/2015 - 03/2012
2	Astrocytoma (Pilocytic Astrocytoma) 07/2014 - 03/2006
2	Myofibrillar Myopathy 03/2014 - 01/2013
1	Ulcerative Colitis 01/2021
1	Rupture 01/2018
1	Infarction (Infarctions) 01/2018
1	Cholestasis 01/2018
1	Cardiomyopathies (Cardiomyopathy) 06/2015
1	Urinary Bladder Neoplasms (Bladder Cancer) 04/2014
1	Neoplasm Metastasis (Metastasis) 04/2014
1	Pathological Protein Aggregation 03/2014
1	Pancreatitis 01/2014
1	Adenocarcinoma 11/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2013
1	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 01/2013
1	Sarcoma (Soft Tissue Sarcoma) 03/2012
1	Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital) 12/2011
1	Dystonia musculorum deformans type 1 10/2008
1	Skin Diseases (Skin Disease) 03/2008
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 03/2007
1	Alexander Disease (Alexander's Disease) 03/2006
1	Nervous System Diseases (Neurological Disorders) 03/2006
1	Glioma (Gliomas) 11/2005
1	Inborn Genetic Diseases (Disease, Hereditary) 02/2003
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2002
1	Autosomal Recessive Epidermolysis Bullosa Simplex 06/2002

Drug/Important Bio-Agent (IBA)

32	PlectinIBA 03/2022 - 01/2002
13	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2004
5	DesminIBA 03/2014 - 06/2002
4	Keratins (Keratin)IBA 01/2018 - 11/2010
4	Protein Isoforms (Isoforms)IBA 06/2015 - 02/2003
2	epiplakinIBA 06/2015 - 01/2014
2	VimentinIBA 04/2014 - 10/2008
1	Laminin (Merosin)IBA 07/2014
1	IntegrinsIBA 07/2014
1	Actins (F Actin)IBA 04/2014
1	CeruletideIBA 01/2014
1	Biomarkers (Surrogate Marker)IBA 11/2013
1	Glucose (Dextrose)FDA LinkGeneric 06/2013
1	Protein AggregatesIBA 01/2013
1	RNA Precursors (Precursor, mRNA)IBA 03/2012
1	Carrier Proteins (Binding Protein)IBA 11/2010
1	Leucine (L-Leucine)FDA Link 03/2008
1	Peptides (Polypeptides)IBA 03/2008
1	Nonsense Codon (Nonsense Mutation)IBA 03/2008
1	Codon (Codons)IBA 03/2008
1	Protein Kinases (Protein Kinase)IBA 08/2006
1	Mitogen-Activated Protein Kinase 3IBA 08/2006
1	Glial Fibrillary Acidic ProteinIBA 03/2006
1	RNA (Ribonucleic Acid)IBA 11/2005
1	AntibodiesIBA 01/2002

Therapy/Procedure

1	Oral Administration 01/2017
1	Therapeutics 02/2003